Skin lesions, anaphylaxis, diarrhea?
Suspect systemic mastocytosis (SM)
Symptoms of SM can mimic other disorders
Select each circle to see how these disorders are different than SM
Mast cell activation syndrome
Review case studies to see how high-sensitivity KIT D816V testing can help confirm SM6
High-sensitivity KIT D816V testing can be used as a first step to evaluate SM upon clinical suspicion6
Additional testing is required for diagnosis and subtyping.
Test for a leading indicator in diagnosis of SM6
High-sensitivity KIT D816V testing
(eg, ASO-qPCR or ddPCR)6
KIT D816V is the main driver of disease in ~95% of SM cases11-13
Patients who test positivefor KIT D816V using high-sensitivity KIT testing have an increased likelihood of SM6,11-13
Serum tryptase should always be measured in patients withsuspected SM.14
Did you know?
Low-sensitivity assays may fail to detect the KIT D816V mutation and potentially prolong diagnosis6FIND A LAB
Explore case studies of the types of patients
you may see in your practice
The profiles below are examples of different patient types, which may help you recognize patients in your practice who may be at risk of SM. Patient profiles are fictionalized through review of published literature and are not actual patients.
Select each of the cases belowto learn more
Screen suspected patients
high-sensitivity KIT D816V assays